' + emailE + '<\/a>') It is appropriate for emission measurements of brick kilns, and other large and small scale industrial combustion sources with and without exhaust stacks. Which one if the following approaches is in use in Canada by participants in the CCAC Program? Rat Room Shoe Box Changes Pages1-3. within 20 s), rats spent 13 s in isoflurane but only 1 s in CO 2. CCAC resources. AVMA Guidelines for the Euthanasia of Animals: 2020 edition; CCAC guidelines on "Choosing an appropriate endpoint in experiments using animals for research, teaching and testing". CCAC guidelines establish the basic requirements for each institutional program within the Canadian system of oversight of animal ethics and care. Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. Physiological normal values (Depends on age, strain, health status, type of anesthesia, etc.) // , Certificate of GAP – Good Animal Practice, National and International Three Rs Centres, Three Rs of Humane Animal Experimentation, Laboratory Animals Used in Biomedical Research, CCAC Certificate of GAP – Good Animal Practice. Enrichment opportunities include features to promote activity, substrates for burrowing, structures to facilitate hiding or avoidance, objects to chew, variety in food, and foraging opportunities. Subcutaneous (SC or SQ) Injection in Rats and Mice SOP Purpose This Standard Operating Procedure (SOP) describes the procedure of subcutaneous injections into rats and mice. Approach-avoidance testing Approach-avoidance testing allows researchers to compare rats’ motivation for a reward against their motivation to avoid gas exposure. The CCAC guidelines: Rats, states that the basic needs include group housing, shelters, and sufficient space to accommodate these elements and the expression of behaviors important to rat welfare. (2011) National Research Council, USA Guidelines for the Survival Bleeding of Mice and Rats. Alberta Government, Agriculture and Rural Development (2007) Firm Steps: Identifying Lameness in Dairy Cattle.Edmonton AB: Alberta Agriculture and Food. RAT BREEDING COLONY MANAGEMENT SOP 609.01 – Rat Breeding Colony Management Page 1 of 4 1. Email: When using oil or viscous gel adjuvant (e.g., FCA) in rabbits, mice or rats, SC is the recommended route. The guidelines document further states that inhalant anesthetics have also been found to … Rats spent an average of 47 s in cages filled with air. The black rat is occasionally found in laboratory colonies, although rarely used in either biomedical or behavioral research. Policies pertaining to the Assessment and Certification program can be found in the Certification section. h��V{lS�?��3Əkǐ�Iӛpq��[��AR�. Standard operating procedures, policies, and guidelines help educate individuals on the proper and current techniques accepted. This Standard Operating Procedure (SOP) describes the procedure of orally dosing rats and mice. Skinner's study of behavior in rats was conducted under carefully controlled laboratory conditions Summary of Guidelines CCAC guidelines: Rats 3 3. 0 190 O'Connor St, Suite 800 Intraperitoneal (IP) Injection in Rats and Mice SOP Page 2 of 4 Procedure 1. j�\����@�Ny���N�1�����o�� Oral Dosing (Gavage) in Adult Mice and Rats SOP . 1989. General Guidelines. This guidelines document, along with its associated frequently asked questions , addresses conditions normally present in laboratories housing rats, and provides a framework for the implementation of evidence-based practices, with the aim of improving the welfare of rats. As the guidelines are updated, they will be removed from this Guide and the new guidelines will be posted on the CCAC website under the appropriate heading. %%EOF Responsibility: Technologists . o@P`�YzLs�ƊN0D���Up�8���"�?5�C�C�y��P��"��"�9���(�Ph9�� ��w,� {�Ҽ_� *�\�;q��lH��� CCAC guidelines: Rats 1 PREFACE The Canadian Council on Animal Care (CCAC) is the national peer-review organization responsible for setting and maintaining standards for the ethics and care of animals in science throughout Canada. RESPONSIBILITY Principal investigator (PI) and their research staff, animal care staff and veterinary care staff. The cotton rat and the kangaroo rat are both indigenous to North America and belong to the Cricetidae, a separate family from that of the black and Norway rats, which are rodents belonging to the Muridae family. 2. Canadian Council on Animal Care. Daily Ottawa, ON, K2P 2R3 : ��in3���NH���nxˡn��՚��.�~ �BZ�8% s��.�nS� ���!�E����*�����ߢ�Yx�QE�|�R|��)����H��>w\���{I���t�z>Ҭ��ԟB3�iCfP�W���[��$�,|�Щ��N����_��9������6:� �Y��c�~հp0���O�:a���w��ӠM,��Y^-I��oɿYU�+'w���#9�3�#yd߮w�����x�>��5}��������/�{ Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. endstream endobj 4129 0 obj <>/Metadata 377 0 R/Names 4147 0 R/OpenAction 4130 0 R/Outlines 867 0 R/PageLayout/OneColumn/Pages 4101 0 R/StructTreeRoot 1082 0 R/Type/Catalog/ViewerPreferences<>>> endobj 4130 0 obj <> endobj 4131 0 obj <. Experimental procedures involving the use of animals in this study were approved by the University Animal Care Committee (UACC) of Queen's University and complied with the guidelines of the Canadian Council of Animal Care (CCAC). The CCAC guidelines: Rats (CCAC, 2020) note that exposing rats to carbon dioxide for euthanasia is likely to cause pain and distress (Leach et al., 2004; Moody et al., 2014). Biological effects of blood loss: implications for sampling volumes and techniques. ... Rat 23‐25g < 10 ml/kg i.e. Materials. Ninety percent of these are rats, mice, fish, and fowl. jo�;���S |�����Y\*hdE�wQ��$0��D5�կ�=����A8�E����29�r�4 Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. CCAC resources. Broom. 2. Three Rs information and additional resources such as frequently asked questions (FAQs) are intended to support the implementation of the guidelines and to encourage institutions to evaluate new practices to enhance their animal ethics and care programs. methods, to achieve “euthanasia”, for rats and other laboratory animals are ongoing, as reflected in recent updates to the Canadian Council on Animal Care (CCAC) and American Veterinary Medical Association (AVMA) eu-thanasia guidelines [3, 4]. Guidelines for the use of animals in cancer research This is a selection of guidelines in the public domain that address the care and use of animals in cancer research, including the issue of … This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. the CCAC program are discussed in more detail in following sections. The main conflict of the story is when rats living in the city dump is mutated (from gases) Construction Cost Summary Template and wreaks havoc on the citizens of the city. Goals for successful euthanasia include techniques requiring minimal restraint, simplicity DZn��*U@��g �eb�xɟ+_2012l ���Hs�?ç�� *CU The Ratnoze is specialized for measuring solid fuel combustion emissions. Disinfectant: Lemon Quat TM, U974. 2010; McGuill MW, Rowan AN. This bibliography was generated on Cite This For Me on Tuesday, January 27, 2015 Rats Mice. The CCAC conducts assessment visits to each participating institution using animals. The guidelines contained within the Guide to Care and Use of Experimental Animals, vol 1, 2nd edition (1993) are currently being revised. Surveillance over the use of experimental animals, including wild vertebrates and invertebrates such as octopi and squid, is the responsibility of the Canadian Council on Animal Care (CCAC), a national, voluntary peer … Paper towel. %PDF-1.4 %���� e����7+���ob��/~"p��/���b���9��_A3)Q���K����:{L7\'V6���Y�f.pH'b�.S��Iɻw�(�f��=@+]��j�1cm����z�p@��.wZ�S��|{�]��W��i�>ѣp���f���K� 3. The CCAC guidelines: Rats provides information for investigators, animal care committees, facility manag- 4165 0 obj <>stream Y�)�f'�b T΍k ,��-��t�{8����\'L�V)�H)U=��l��}ߵ�8��Ǵ�v��s����w~�\� Zb zX�� ��g\H� @#DBZ�� h�D���] �9h� ^���9[CY?�|�b\�*AR��I�9x*! American Association of Swine Veterinarians (AASV) and National Pork Board (2008) On-Farm Euthanasia of Swine: Recommendations for the Producer.Des Moines IA: National Pork Board. The CCAC comprises 22 member organizations, whose presentatives include scientists, educators, veterinarians and delegates from industry and the animal welfare movement. Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. Dust Pan. The CCAC euthanasia guideline (CCAC 2010) for animals used in science (all vertebrates and cephalopods) similarly requires killing methods to be “as distress free and painless as possible” (p.7) and result in rapid loss of consciousness. endstream endobj startxref 4128 0 obj <> endobj Normal core body temperature 37.5 –38.5oC Normal core body temperature 37.0 – 38.0oC Normal heart rate range 260 – 600 bpm Normal heart rate range 350 - 800 bpm. [CDATA[ �Z0:Bn�@q�-�^~�uX�OdcHކ��P?x�T�3i�//���.�kb����d{�$u�a&F�TLR�m8�{`e�Ǯ@]kX��!����[��t��`�z�H��˔���f� �`3��'��g���^�[��/��LI�z��F��2^�{�R���8��q�,�H[*��Spˌ�� ����Txw{�U5&�n��-e��5��6�]�΢���.���6���mv��m+���Y���[����=�$���a�e']R��X=/���BaQ��X���MxF!OCV��uOx�������G��x=I�J��Ęݧ����u�L�1�?�gd8\M��D1Y漶�s�d��9B�7o�X��7�B����0���.2,V�%R/�%y�UN���V�cBDUr}���޴�Y��!�Ӂ���^�[�]����:�w� �T%��N�S��=����9�{n�,��)�����۠ �{ֻ��Y�z��>�&^�6��3�y�;�Č51����^�����o��*��_ʱgˆ�Ǜg�ү�Uda�C��4:՚�x"����u*0��[� �USQ��}Y�����B�� �J�0?��Uc�����U�h廬}�Gx���e'&2������«�.���Xjrq�k �L 8%)�' Tel: 613-238-4031 (1998) Canadian Council on Animal Care, Canada; Guide for the care and use of laboratory animals. Purpose: to ensure each rat room and shoebox cage is maintained daily, weekly, and monthly care of rat rooms. rat to a temperature around 400C by placing the animal into a thermostatically warmed 'hot-box' (Conybeare et al., 1988), warming the tail under a heating lamp (Waynforth and Flecknell, 1992) or holding the tail in warm water for 1—2 minutes (Fallon, 1996) can induce tail vein dilation. Draw up, into the syringe and needle, the amount of solution to be administered. It is recommended to keep gestating and lactating rat dams, and pups up to 3‐4 weeks old, at the higher end of the recommended temperature range (24‐26C), as they have reduced thermoregulatory ability. Guidelines of the CCAC Since the first Guide to the Care and Use of Experimental Animals was published in 1968, the guidelines of the CCAC have steadily evolved in response to new information or … Assessments are based on several documents, including the CCAC guidelines and policies. The guidelines are based on expert peer advice and current interpretation of … Policy: Laurentian University and CCAC guidelines and Regulations. h�bbd```b`��"�A$� �d1��� ��L~�l�΀��� �,�� CCAC guidelines are intended to provide assistance in the implementation of Russell and Burch’s Three Rs (Replacement, Reduction and Refinement) principles for animals in science (Russell and Burch, 1959). In general terms the CCAC recommends that ... 17mm, width 17mm) tumour for rats. Pail. 4146 0 obj <>/Filter/FlateDecode/ID[<90C47C91D84E48C49C31241C391AB876><55AB78EB64346C4BA606F51FF4F157B1>]/Index[4128 38]/Info 4127 0 R/Length 102/Prev 1528554/Root 4129 0 R/Size 4166/Type/XRef/W[1 3 1]>>stream ILAR Journal Vol 31, Issue 4, p. 5-20; Rat - Blood draw video (saphenous vein, cardiac puncture) !�v���h��p��P�- Rats were sacrificed on the 7th and 14th days for pathological examination of the wound. Viscous adjuvants should never be given IV due to the risk of thrombosis and pulmonary embolism. emailE=('ccac@' + 'ccac.ca') MATERIALS 3.1. This is a user guide for the Ratnoze portable sampling system. �R�q�ei��2��&���}�h�� ���$�܏�t]���u��=�~��|n;A?���/����)�/��?�2,�r��d��\�����s�����'�%O�TOJ�bӹ�œ)�.�O'L���]�J���f��-"?��D�žL5m����̲�^ү̩�( e�����\hj�Ɨ�1sKH�f��|�b���QΒ�u�H�R� }�����@ZԪ�%Kf���!Ͻ�Pŋ"����������1�PP�&W��Dž/��!vp*����+�ETPt�����$�������H|�����s�� oÃc z� CCAC Guidelines: The current CCAC guidelines indicate that for cancer research the experiment must be designed with endpoints that minimize the potential for pain and/or distress. This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. Aqueous adjuvants (or antigens without adjuvant) are usually given SC, IP, or IV to rats and mice, or SC, IM, or IV in rabbits. 0 �'� CCAC Publishes New Guidelines on Rats The CCAC guidelines: Rats is now available. In studies assessing rat aversion to euthanasia agents, These are the sources and citations used to research Chronic Restraint Stress in Rats. Compliance with CCAC guidelines and policies is a requirement to receive a CCAC Certificate of GAP – Good Animal Practice®, as determined by CCAC assessment panels. ... An investigator has developed a thorough analgesic protocol for experimental surgery on rats. When placing rats in a warmed box, it is essential that the Establish the basic requirements for each institutional program within the Canadian system oversight... Ccac recommends that... 17mm, width 17mm ) tumour for rats the syringe and needle, amount... Appropriate for emission measurements of brick kilns, and regulatory standards associated with the conduct of studies conduct! Ottawa, on, K2P 2R3 Tel: 613-238-4031 Fax: 613-238-2837 Email: ' + emailE + '<\/a>') It is appropriate for emission measurements of brick kilns, and other large and small scale industrial combustion sources with and without exhaust stacks. Which one if the following approaches is in use in Canada by participants in the CCAC Program? Rat Room Shoe Box Changes Pages1-3. within 20 s), rats spent 13 s in isoflurane but only 1 s in CO 2. CCAC resources. AVMA Guidelines for the Euthanasia of Animals: 2020 edition; CCAC guidelines on "Choosing an appropriate endpoint in experiments using animals for research, teaching and testing". CCAC guidelines establish the basic requirements for each institutional program within the Canadian system of oversight of animal ethics and care. Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. Physiological normal values (Depends on age, strain, health status, type of anesthesia, etc.) // , Certificate of GAP – Good Animal Practice, National and International Three Rs Centres, Three Rs of Humane Animal Experimentation, Laboratory Animals Used in Biomedical Research, CCAC Certificate of GAP – Good Animal Practice. Enrichment opportunities include features to promote activity, substrates for burrowing, structures to facilitate hiding or avoidance, objects to chew, variety in food, and foraging opportunities. Subcutaneous (SC or SQ) Injection in Rats and Mice SOP Purpose This Standard Operating Procedure (SOP) describes the procedure of subcutaneous injections into rats and mice. Approach-avoidance testing Approach-avoidance testing allows researchers to compare rats’ motivation for a reward against their motivation to avoid gas exposure. The CCAC guidelines: Rats, states that the basic needs include group housing, shelters, and sufficient space to accommodate these elements and the expression of behaviors important to rat welfare. (2011) National Research Council, USA Guidelines for the Survival Bleeding of Mice and Rats. Alberta Government, Agriculture and Rural Development (2007) Firm Steps: Identifying Lameness in Dairy Cattle.Edmonton AB: Alberta Agriculture and Food. RAT BREEDING COLONY MANAGEMENT SOP 609.01 – Rat Breeding Colony Management Page 1 of 4 1. Email: When using oil or viscous gel adjuvant (e.g., FCA) in rabbits, mice or rats, SC is the recommended route. The guidelines document further states that inhalant anesthetics have also been found to … Rats spent an average of 47 s in cages filled with air. The black rat is occasionally found in laboratory colonies, although rarely used in either biomedical or behavioral research. Policies pertaining to the Assessment and Certification program can be found in the Certification section. h��V{lS�?��3Əkǐ�Iӛpq��[��AR�. Standard operating procedures, policies, and guidelines help educate individuals on the proper and current techniques accepted. This Standard Operating Procedure (SOP) describes the procedure of orally dosing rats and mice. Skinner's study of behavior in rats was conducted under carefully controlled laboratory conditions Summary of Guidelines CCAC guidelines: Rats 3 3. 0 190 O'Connor St, Suite 800 Intraperitoneal (IP) Injection in Rats and Mice SOP Page 2 of 4 Procedure 1. j�\����@�Ny���N�1�����o�� Oral Dosing (Gavage) in Adult Mice and Rats SOP . 1989. General Guidelines. This guidelines document, along with its associated frequently asked questions , addresses conditions normally present in laboratories housing rats, and provides a framework for the implementation of evidence-based practices, with the aim of improving the welfare of rats. As the guidelines are updated, they will be removed from this Guide and the new guidelines will be posted on the CCAC website under the appropriate heading. %%EOF Responsibility: Technologists . o@P`�YzLs�ƊN0D���Up�8���"�?5�C�C�y��P��"��"�9���(�Ph9�� ��w,� {�Ҽ_� *�\�;q��lH��� CCAC guidelines: Rats 1 PREFACE The Canadian Council on Animal Care (CCAC) is the national peer-review organization responsible for setting and maintaining standards for the ethics and care of animals in science throughout Canada. RESPONSIBILITY Principal investigator (PI) and their research staff, animal care staff and veterinary care staff. The cotton rat and the kangaroo rat are both indigenous to North America and belong to the Cricetidae, a separate family from that of the black and Norway rats, which are rodents belonging to the Muridae family. 2. Canadian Council on Animal Care. Daily Ottawa, ON, K2P 2R3 : ��in3���NH���nxˡn��՚��.�~ �BZ�8% s��.�nS� ���!�E����*�����ߢ�Yx�QE�|�R|��)����H��>w\���{I���t�z>Ҭ��ԟB3�iCfP�W���[��$�,|�Щ��N����_��9������6:� �Y��c�~հp0���O�:a���w��ӠM,��Y^-I��oɿYU�+'w���#9�3�#yd߮w�����x�>��5}��������/�{ Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. endstream endobj 4129 0 obj <>/Metadata 377 0 R/Names 4147 0 R/OpenAction 4130 0 R/Outlines 867 0 R/PageLayout/OneColumn/Pages 4101 0 R/StructTreeRoot 1082 0 R/Type/Catalog/ViewerPreferences<>>> endobj 4130 0 obj <> endobj 4131 0 obj <. Experimental procedures involving the use of animals in this study were approved by the University Animal Care Committee (UACC) of Queen's University and complied with the guidelines of the Canadian Council of Animal Care (CCAC). The CCAC guidelines: Rats (CCAC, 2020) note that exposing rats to carbon dioxide for euthanasia is likely to cause pain and distress (Leach et al., 2004; Moody et al., 2014). Biological effects of blood loss: implications for sampling volumes and techniques. ... Rat 23‐25g < 10 ml/kg i.e. Materials. Ninety percent of these are rats, mice, fish, and fowl. jo�;���S |�����Y\*hdE�wQ��$0��D5�կ�=����A8�E����29�r�4 Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. CCAC resources. Broom. 2. Three Rs information and additional resources such as frequently asked questions (FAQs) are intended to support the implementation of the guidelines and to encourage institutions to evaluate new practices to enhance their animal ethics and care programs. methods, to achieve “euthanasia”, for rats and other laboratory animals are ongoing, as reflected in recent updates to the Canadian Council on Animal Care (CCAC) and American Veterinary Medical Association (AVMA) eu-thanasia guidelines [3, 4]. Guidelines for the use of animals in cancer research This is a selection of guidelines in the public domain that address the care and use of animals in cancer research, including the issue of … This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. the CCAC program are discussed in more detail in following sections. The main conflict of the story is when rats living in the city dump is mutated (from gases) Construction Cost Summary Template and wreaks havoc on the citizens of the city. Goals for successful euthanasia include techniques requiring minimal restraint, simplicity DZn��*U@��g �eb�xɟ+_2012l ���Hs�?ç�� *CU The Ratnoze is specialized for measuring solid fuel combustion emissions. Disinfectant: Lemon Quat TM, U974. 2010; McGuill MW, Rowan AN. This bibliography was generated on Cite This For Me on Tuesday, January 27, 2015 Rats Mice. The CCAC conducts assessment visits to each participating institution using animals. The guidelines contained within the Guide to Care and Use of Experimental Animals, vol 1, 2nd edition (1993) are currently being revised. Surveillance over the use of experimental animals, including wild vertebrates and invertebrates such as octopi and squid, is the responsibility of the Canadian Council on Animal Care (CCAC), a national, voluntary peer … Paper towel. %PDF-1.4 %���� e����7+���ob��/~"p��/���b���9��_A3)Q���K����:{L7\'V6���Y�f.pH'b�.S��Iɻw�(�f��=@+]��j�1cm����z�p@��.wZ�S��|{�]��W��i�>ѣp���f���K� 3. The CCAC guidelines: Rats provides information for investigators, animal care committees, facility manag- 4165 0 obj <>stream Y�)�f'�b T΍k ,��-��t�{8����\'L�V)�H)U=��l��}ߵ�8��Ǵ�v��s����w~�\� Zb zX�� ��g\H� @#DBZ�� h�D���] �9h� ^���9[CY?�|�b\�*AR��I�9x*! American Association of Swine Veterinarians (AASV) and National Pork Board (2008) On-Farm Euthanasia of Swine: Recommendations for the Producer.Des Moines IA: National Pork Board. The CCAC comprises 22 member organizations, whose presentatives include scientists, educators, veterinarians and delegates from industry and the animal welfare movement. Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. Dust Pan. The CCAC euthanasia guideline (CCAC 2010) for animals used in science (all vertebrates and cephalopods) similarly requires killing methods to be “as distress free and painless as possible” (p.7) and result in rapid loss of consciousness. endstream endobj startxref 4128 0 obj <> endobj Normal core body temperature 37.5 –38.5oC Normal core body temperature 37.0 – 38.0oC Normal heart rate range 260 – 600 bpm Normal heart rate range 350 - 800 bpm. [CDATA[ �Z0:Bn�@q�-�^~�uX�OdcHކ��P?x�T�3i�//���.�kb����d{�$u�a&F�TLR�m8�{`e�Ǯ@]kX��!����[��t��`�z�H��˔���f� �`3��'��g���^�[��/��LI�z��F��2^�{�R���8��q�,�H[*��Spˌ�� ����Txw{�U5&�n��-e��5��6�]�΢���.���6���mv��m+���Y���[����=�$���a�e']R��X=/���BaQ��X���MxF!OCV��uOx�������G��x=I�J��Ęݧ����u�L�1�?�gd8\M��D1Y漶�s�d��9B�7o�X��7�B����0���.2,V�%R/�%y�UN���V�cBDUr}���޴�Y��!�Ӂ���^�[�]����:�w� �T%��N�S��=����9�{n�,��)�����۠ �{ֻ��Y�z��>�&^�6��3�y�;�Č51����^�����o��*��_ʱgˆ�Ǜg�ү�Uda�C��4:՚�x"����u*0��[� �USQ��}Y�����B�� �J�0?��Uc�����U�h廬}�Gx���e'&2������«�.���Xjrq�k �L 8%)�' Tel: 613-238-4031 (1998) Canadian Council on Animal Care, Canada; Guide for the care and use of laboratory animals. Purpose: to ensure each rat room and shoebox cage is maintained daily, weekly, and monthly care of rat rooms. rat to a temperature around 400C by placing the animal into a thermostatically warmed 'hot-box' (Conybeare et al., 1988), warming the tail under a heating lamp (Waynforth and Flecknell, 1992) or holding the tail in warm water for 1—2 minutes (Fallon, 1996) can induce tail vein dilation. Draw up, into the syringe and needle, the amount of solution to be administered. It is recommended to keep gestating and lactating rat dams, and pups up to 3‐4 weeks old, at the higher end of the recommended temperature range (24‐26C), as they have reduced thermoregulatory ability. Guidelines of the CCAC Since the first Guide to the Care and Use of Experimental Animals was published in 1968, the guidelines of the CCAC have steadily evolved in response to new information or … Assessments are based on several documents, including the CCAC guidelines and policies. The guidelines are based on expert peer advice and current interpretation of … Policy: Laurentian University and CCAC guidelines and Regulations. h�bbd```b`��"�A$� �d1��� ��L~�l�΀��� �,�� CCAC guidelines are intended to provide assistance in the implementation of Russell and Burch’s Three Rs (Replacement, Reduction and Refinement) principles for animals in science (Russell and Burch, 1959). In general terms the CCAC recommends that ... 17mm, width 17mm) tumour for rats. Pail. 4146 0 obj <>/Filter/FlateDecode/ID[<90C47C91D84E48C49C31241C391AB876><55AB78EB64346C4BA606F51FF4F157B1>]/Index[4128 38]/Info 4127 0 R/Length 102/Prev 1528554/Root 4129 0 R/Size 4166/Type/XRef/W[1 3 1]>>stream ILAR Journal Vol 31, Issue 4, p. 5-20; Rat - Blood draw video (saphenous vein, cardiac puncture) !�v���h��p��P�- Rats were sacrificed on the 7th and 14th days for pathological examination of the wound. Viscous adjuvants should never be given IV due to the risk of thrombosis and pulmonary embolism. emailE=('ccac@' + 'ccac.ca') MATERIALS 3.1. This is a user guide for the Ratnoze portable sampling system. �R�q�ei��2��&���}�h�� ���$�܏�t]���u��=�~��|n;A?���/����)�/��?�2,�r��d��\�����s�����'�%O�TOJ�bӹ�œ)�.�O'L���]�J���f��-"?��D�žL5m����̲�^ү̩�( e�����\hj�Ɨ�1sKH�f��|�b���QΒ�u�H�R� }�����@ZԪ�%Kf���!Ͻ�Pŋ"����������1�PP�&W��Dž/��!vp*����+�ETPt�����$�������H|�����s�� oÃc z� CCAC Guidelines: The current CCAC guidelines indicate that for cancer research the experiment must be designed with endpoints that minimize the potential for pain and/or distress. This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. Aqueous adjuvants (or antigens without adjuvant) are usually given SC, IP, or IV to rats and mice, or SC, IM, or IV in rabbits. 0 �'� CCAC Publishes New Guidelines on Rats The CCAC guidelines: Rats is now available. In studies assessing rat aversion to euthanasia agents, These are the sources and citations used to research Chronic Restraint Stress in Rats. Compliance with CCAC guidelines and policies is a requirement to receive a CCAC Certificate of GAP – Good Animal Practice®, as determined by CCAC assessment panels. ... An investigator has developed a thorough analgesic protocol for experimental surgery on rats. When placing rats in a warmed box, it is essential that the Establish the basic requirements for each institutional program within the Canadian system oversight... Ccac recommends that... 17mm, width 17mm ) tumour for rats the syringe and needle, amount... Appropriate for emission measurements of brick kilns, and regulatory standards associated with the conduct of studies conduct! Ottawa, on, K2P 2R3 Tel: 613-238-4031 Fax: 613-238-2837 Email: ' + emailE + '<\/a>') It is appropriate for emission measurements of brick kilns, and other large and small scale industrial combustion sources with and without exhaust stacks. Which one if the following approaches is in use in Canada by participants in the CCAC Program? Rat Room Shoe Box Changes Pages1-3. within 20 s), rats spent 13 s in isoflurane but only 1 s in CO 2. CCAC resources. AVMA Guidelines for the Euthanasia of Animals: 2020 edition; CCAC guidelines on "Choosing an appropriate endpoint in experiments using animals for research, teaching and testing". CCAC guidelines establish the basic requirements for each institutional program within the Canadian system of oversight of animal ethics and care. Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. Physiological normal values (Depends on age, strain, health status, type of anesthesia, etc.) // , Certificate of GAP – Good Animal Practice, National and International Three Rs Centres, Three Rs of Humane Animal Experimentation, Laboratory Animals Used in Biomedical Research, CCAC Certificate of GAP – Good Animal Practice. Enrichment opportunities include features to promote activity, substrates for burrowing, structures to facilitate hiding or avoidance, objects to chew, variety in food, and foraging opportunities. Subcutaneous (SC or SQ) Injection in Rats and Mice SOP Purpose This Standard Operating Procedure (SOP) describes the procedure of subcutaneous injections into rats and mice. Approach-avoidance testing Approach-avoidance testing allows researchers to compare rats’ motivation for a reward against their motivation to avoid gas exposure. The CCAC guidelines: Rats, states that the basic needs include group housing, shelters, and sufficient space to accommodate these elements and the expression of behaviors important to rat welfare. (2011) National Research Council, USA Guidelines for the Survival Bleeding of Mice and Rats. Alberta Government, Agriculture and Rural Development (2007) Firm Steps: Identifying Lameness in Dairy Cattle.Edmonton AB: Alberta Agriculture and Food. RAT BREEDING COLONY MANAGEMENT SOP 609.01 – Rat Breeding Colony Management Page 1 of 4 1. Email: When using oil or viscous gel adjuvant (e.g., FCA) in rabbits, mice or rats, SC is the recommended route. The guidelines document further states that inhalant anesthetics have also been found to … Rats spent an average of 47 s in cages filled with air. The black rat is occasionally found in laboratory colonies, although rarely used in either biomedical or behavioral research. Policies pertaining to the Assessment and Certification program can be found in the Certification section. h��V{lS�?��3Əkǐ�Iӛpq��[��AR�. Standard operating procedures, policies, and guidelines help educate individuals on the proper and current techniques accepted. This Standard Operating Procedure (SOP) describes the procedure of orally dosing rats and mice. Skinner's study of behavior in rats was conducted under carefully controlled laboratory conditions Summary of Guidelines CCAC guidelines: Rats 3 3. 0 190 O'Connor St, Suite 800 Intraperitoneal (IP) Injection in Rats and Mice SOP Page 2 of 4 Procedure 1. j�\����@�Ny���N�1�����o�� Oral Dosing (Gavage) in Adult Mice and Rats SOP . 1989. General Guidelines. This guidelines document, along with its associated frequently asked questions , addresses conditions normally present in laboratories housing rats, and provides a framework for the implementation of evidence-based practices, with the aim of improving the welfare of rats. As the guidelines are updated, they will be removed from this Guide and the new guidelines will be posted on the CCAC website under the appropriate heading. %%EOF Responsibility: Technologists . o@P`�YzLs�ƊN0D���Up�8���"�?5�C�C�y��P��"��"�9���(�Ph9�� ��w,� {�Ҽ_� *�\�;q��lH��� CCAC guidelines: Rats 1 PREFACE The Canadian Council on Animal Care (CCAC) is the national peer-review organization responsible for setting and maintaining standards for the ethics and care of animals in science throughout Canada. RESPONSIBILITY Principal investigator (PI) and their research staff, animal care staff and veterinary care staff. The cotton rat and the kangaroo rat are both indigenous to North America and belong to the Cricetidae, a separate family from that of the black and Norway rats, which are rodents belonging to the Muridae family. 2. Canadian Council on Animal Care. Daily Ottawa, ON, K2P 2R3 : ��in3���NH���nxˡn��՚��.�~ �BZ�8% s��.�nS� ���!�E����*�����ߢ�Yx�QE�|�R|��)����H��>w\���{I���t�z>Ҭ��ԟB3�iCfP�W���[��$�,|�Щ��N����_��9������6:� �Y��c�~հp0���O�:a���w��ӠM,��Y^-I��oɿYU�+'w���#9�3�#yd߮w�����x�>��5}��������/�{ Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. endstream endobj 4129 0 obj <>/Metadata 377 0 R/Names 4147 0 R/OpenAction 4130 0 R/Outlines 867 0 R/PageLayout/OneColumn/Pages 4101 0 R/StructTreeRoot 1082 0 R/Type/Catalog/ViewerPreferences<>>> endobj 4130 0 obj <> endobj 4131 0 obj <. Experimental procedures involving the use of animals in this study were approved by the University Animal Care Committee (UACC) of Queen's University and complied with the guidelines of the Canadian Council of Animal Care (CCAC). The CCAC guidelines: Rats (CCAC, 2020) note that exposing rats to carbon dioxide for euthanasia is likely to cause pain and distress (Leach et al., 2004; Moody et al., 2014). Biological effects of blood loss: implications for sampling volumes and techniques. ... Rat 23‐25g < 10 ml/kg i.e. Materials. Ninety percent of these are rats, mice, fish, and fowl. jo�;���S |�����Y\*hdE�wQ��$0��D5�կ�=����A8�E����29�r�4 Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. CCAC resources. Broom. 2. Three Rs information and additional resources such as frequently asked questions (FAQs) are intended to support the implementation of the guidelines and to encourage institutions to evaluate new practices to enhance their animal ethics and care programs. methods, to achieve “euthanasia”, for rats and other laboratory animals are ongoing, as reflected in recent updates to the Canadian Council on Animal Care (CCAC) and American Veterinary Medical Association (AVMA) eu-thanasia guidelines [3, 4]. Guidelines for the use of animals in cancer research This is a selection of guidelines in the public domain that address the care and use of animals in cancer research, including the issue of … This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. the CCAC program are discussed in more detail in following sections. The main conflict of the story is when rats living in the city dump is mutated (from gases) Construction Cost Summary Template and wreaks havoc on the citizens of the city. Goals for successful euthanasia include techniques requiring minimal restraint, simplicity DZn��*U@��g �eb�xɟ+_2012l ���Hs�?ç�� *CU The Ratnoze is specialized for measuring solid fuel combustion emissions. Disinfectant: Lemon Quat TM, U974. 2010; McGuill MW, Rowan AN. This bibliography was generated on Cite This For Me on Tuesday, January 27, 2015 Rats Mice. The CCAC conducts assessment visits to each participating institution using animals. The guidelines contained within the Guide to Care and Use of Experimental Animals, vol 1, 2nd edition (1993) are currently being revised. Surveillance over the use of experimental animals, including wild vertebrates and invertebrates such as octopi and squid, is the responsibility of the Canadian Council on Animal Care (CCAC), a national, voluntary peer … Paper towel. %PDF-1.4 %���� e����7+���ob��/~"p��/���b���9��_A3)Q���K����:{L7\'V6���Y�f.pH'b�.S��Iɻw�(�f��=@+]��j�1cm����z�p@��.wZ�S��|{�]��W��i�>ѣp���f���K� 3. The CCAC guidelines: Rats provides information for investigators, animal care committees, facility manag- 4165 0 obj <>stream Y�)�f'�b T΍k ,��-��t�{8����\'L�V)�H)U=��l��}ߵ�8��Ǵ�v��s����w~�\� Zb zX�� ��g\H� @#DBZ�� h�D���] �9h� ^���9[CY?�|�b\�*AR��I�9x*! American Association of Swine Veterinarians (AASV) and National Pork Board (2008) On-Farm Euthanasia of Swine: Recommendations for the Producer.Des Moines IA: National Pork Board. The CCAC comprises 22 member organizations, whose presentatives include scientists, educators, veterinarians and delegates from industry and the animal welfare movement. Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. Dust Pan. The CCAC euthanasia guideline (CCAC 2010) for animals used in science (all vertebrates and cephalopods) similarly requires killing methods to be “as distress free and painless as possible” (p.7) and result in rapid loss of consciousness. endstream endobj startxref 4128 0 obj <> endobj Normal core body temperature 37.5 –38.5oC Normal core body temperature 37.0 – 38.0oC Normal heart rate range 260 – 600 bpm Normal heart rate range 350 - 800 bpm. [CDATA[ �Z0:Bn�@q�-�^~�uX�OdcHކ��P?x�T�3i�//���.�kb����d{�$u�a&F�TLR�m8�{`e�Ǯ@]kX��!����[��t��`�z�H��˔���f� �`3��'��g���^�[��/��LI�z��F��2^�{�R���8��q�,�H[*��Spˌ�� ����Txw{�U5&�n��-e��5��6�]�΢���.���6���mv��m+���Y���[����=�$���a�e']R��X=/���BaQ��X���MxF!OCV��uOx�������G��x=I�J��Ęݧ����u�L�1�?�gd8\M��D1Y漶�s�d��9B�7o�X��7�B����0���.2,V�%R/�%y�UN���V�cBDUr}���޴�Y��!�Ӂ���^�[�]����:�w� �T%��N�S��=����9�{n�,��)�����۠ �{ֻ��Y�z��>�&^�6��3�y�;�Č51����^�����o��*��_ʱgˆ�Ǜg�ү�Uda�C��4:՚�x"����u*0��[� �USQ��}Y�����B�� �J�0?��Uc�����U�h廬}�Gx���e'&2������«�.���Xjrq�k �L 8%)�' Tel: 613-238-4031 (1998) Canadian Council on Animal Care, Canada; Guide for the care and use of laboratory animals. Purpose: to ensure each rat room and shoebox cage is maintained daily, weekly, and monthly care of rat rooms. rat to a temperature around 400C by placing the animal into a thermostatically warmed 'hot-box' (Conybeare et al., 1988), warming the tail under a heating lamp (Waynforth and Flecknell, 1992) or holding the tail in warm water for 1—2 minutes (Fallon, 1996) can induce tail vein dilation. Draw up, into the syringe and needle, the amount of solution to be administered. It is recommended to keep gestating and lactating rat dams, and pups up to 3‐4 weeks old, at the higher end of the recommended temperature range (24‐26C), as they have reduced thermoregulatory ability. Guidelines of the CCAC Since the first Guide to the Care and Use of Experimental Animals was published in 1968, the guidelines of the CCAC have steadily evolved in response to new information or … Assessments are based on several documents, including the CCAC guidelines and policies. The guidelines are based on expert peer advice and current interpretation of … Policy: Laurentian University and CCAC guidelines and Regulations. h�bbd```b`��"�A$� �d1��� ��L~�l�΀��� �,�� CCAC guidelines are intended to provide assistance in the implementation of Russell and Burch’s Three Rs (Replacement, Reduction and Refinement) principles for animals in science (Russell and Burch, 1959). In general terms the CCAC recommends that ... 17mm, width 17mm) tumour for rats. Pail. 4146 0 obj <>/Filter/FlateDecode/ID[<90C47C91D84E48C49C31241C391AB876><55AB78EB64346C4BA606F51FF4F157B1>]/Index[4128 38]/Info 4127 0 R/Length 102/Prev 1528554/Root 4129 0 R/Size 4166/Type/XRef/W[1 3 1]>>stream ILAR Journal Vol 31, Issue 4, p. 5-20; Rat - Blood draw video (saphenous vein, cardiac puncture) !�v���h��p��P�- Rats were sacrificed on the 7th and 14th days for pathological examination of the wound. Viscous adjuvants should never be given IV due to the risk of thrombosis and pulmonary embolism. emailE=('ccac@' + 'ccac.ca') MATERIALS 3.1. This is a user guide for the Ratnoze portable sampling system. �R�q�ei��2��&���}�h�� ���$�܏�t]���u��=�~��|n;A?���/����)�/��?�2,�r��d��\�����s�����'�%O�TOJ�bӹ�œ)�.�O'L���]�J���f��-"?��D�žL5m����̲�^ү̩�( e�����\hj�Ɨ�1sKH�f��|�b���QΒ�u�H�R� }�����@ZԪ�%Kf���!Ͻ�Pŋ"����������1�PP�&W��Dž/��!vp*����+�ETPt�����$�������H|�����s�� oÃc z� CCAC Guidelines: The current CCAC guidelines indicate that for cancer research the experiment must be designed with endpoints that minimize the potential for pain and/or distress. This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. Aqueous adjuvants (or antigens without adjuvant) are usually given SC, IP, or IV to rats and mice, or SC, IM, or IV in rabbits. 0 �'� CCAC Publishes New Guidelines on Rats The CCAC guidelines: Rats is now available. In studies assessing rat aversion to euthanasia agents, These are the sources and citations used to research Chronic Restraint Stress in Rats. Compliance with CCAC guidelines and policies is a requirement to receive a CCAC Certificate of GAP – Good Animal Practice®, as determined by CCAC assessment panels. ... An investigator has developed a thorough analgesic protocol for experimental surgery on rats. When placing rats in a warmed box, it is essential that the Establish the basic requirements for each institutional program within the Canadian system oversight... Ccac recommends that... 17mm, width 17mm ) tumour for rats the syringe and needle, amount... Appropriate for emission measurements of brick kilns, and regulatory standards associated with the conduct of studies conduct! Ottawa, on, K2P 2R3 Tel: 613-238-4031 Fax: 613-238-2837 Email:

ccac rat guidelines

Purpose . CCAC guidelines establish the basic requirements for each institutional program within the Canadian system of oversight of animal ethics and care. document.write('' + emailE + '<\/a>') It is appropriate for emission measurements of brick kilns, and other large and small scale industrial combustion sources with and without exhaust stacks. Which one if the following approaches is in use in Canada by participants in the CCAC Program? Rat Room Shoe Box Changes Pages1-3. within 20 s), rats spent 13 s in isoflurane but only 1 s in CO 2. CCAC resources. AVMA Guidelines for the Euthanasia of Animals: 2020 edition; CCAC guidelines on "Choosing an appropriate endpoint in experiments using animals for research, teaching and testing". CCAC guidelines establish the basic requirements for each institutional program within the Canadian system of oversight of animal ethics and care. Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. Physiological normal values (Depends on age, strain, health status, type of anesthesia, etc.) // , Certificate of GAP – Good Animal Practice, National and International Three Rs Centres, Three Rs of Humane Animal Experimentation, Laboratory Animals Used in Biomedical Research, CCAC Certificate of GAP – Good Animal Practice. Enrichment opportunities include features to promote activity, substrates for burrowing, structures to facilitate hiding or avoidance, objects to chew, variety in food, and foraging opportunities. Subcutaneous (SC or SQ) Injection in Rats and Mice SOP Purpose This Standard Operating Procedure (SOP) describes the procedure of subcutaneous injections into rats and mice. Approach-avoidance testing Approach-avoidance testing allows researchers to compare rats’ motivation for a reward against their motivation to avoid gas exposure. The CCAC guidelines: Rats, states that the basic needs include group housing, shelters, and sufficient space to accommodate these elements and the expression of behaviors important to rat welfare. (2011) National Research Council, USA Guidelines for the Survival Bleeding of Mice and Rats. Alberta Government, Agriculture and Rural Development (2007) Firm Steps: Identifying Lameness in Dairy Cattle.Edmonton AB: Alberta Agriculture and Food. RAT BREEDING COLONY MANAGEMENT SOP 609.01 – Rat Breeding Colony Management Page 1 of 4 1. Email: When using oil or viscous gel adjuvant (e.g., FCA) in rabbits, mice or rats, SC is the recommended route. The guidelines document further states that inhalant anesthetics have also been found to … Rats spent an average of 47 s in cages filled with air. The black rat is occasionally found in laboratory colonies, although rarely used in either biomedical or behavioral research. Policies pertaining to the Assessment and Certification program can be found in the Certification section. h��V{lS�?��3Əkǐ�Iӛpq��[��AR�. Standard operating procedures, policies, and guidelines help educate individuals on the proper and current techniques accepted. This Standard Operating Procedure (SOP) describes the procedure of orally dosing rats and mice. Skinner's study of behavior in rats was conducted under carefully controlled laboratory conditions Summary of Guidelines CCAC guidelines: Rats 3 3. 0 190 O'Connor St, Suite 800 Intraperitoneal (IP) Injection in Rats and Mice SOP Page 2 of 4 Procedure 1. j�\����@�Ny���N�1�����o�� Oral Dosing (Gavage) in Adult Mice and Rats SOP . 1989. General Guidelines. This guidelines document, along with its associated frequently asked questions , addresses conditions normally present in laboratories housing rats, and provides a framework for the implementation of evidence-based practices, with the aim of improving the welfare of rats. As the guidelines are updated, they will be removed from this Guide and the new guidelines will be posted on the CCAC website under the appropriate heading. %%EOF Responsibility: Technologists . o@P`�YzLs�ƊN0D���Up�8���"�?5�C�C�y��P��"��"�9���(�Ph9�� ��w,� {�Ҽ_� *�\�;q��lH��� CCAC guidelines: Rats 1 PREFACE The Canadian Council on Animal Care (CCAC) is the national peer-review organization responsible for setting and maintaining standards for the ethics and care of animals in science throughout Canada. RESPONSIBILITY Principal investigator (PI) and their research staff, animal care staff and veterinary care staff. The cotton rat and the kangaroo rat are both indigenous to North America and belong to the Cricetidae, a separate family from that of the black and Norway rats, which are rodents belonging to the Muridae family. 2. Canadian Council on Animal Care. Daily Ottawa, ON, K2P 2R3 : ��in3���NH���nxˡn��՚��.�~ �BZ�8% s��.�nS� ���!�E����*�����ߢ�Yx�QE�|�R|��)����H��>w\���{I���t�z>Ҭ��ԟB3�iCfP�W���[��$�,|�Щ��N����_��9������6:� �Y��c�~հp0���O�:a���w��ӠM,��Y^-I��oɿYU�+'w���#9�3�#yd߮w�����x�>��5}��������/�{ Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. endstream endobj 4129 0 obj <>/Metadata 377 0 R/Names 4147 0 R/OpenAction 4130 0 R/Outlines 867 0 R/PageLayout/OneColumn/Pages 4101 0 R/StructTreeRoot 1082 0 R/Type/Catalog/ViewerPreferences<>>> endobj 4130 0 obj <> endobj 4131 0 obj <. Experimental procedures involving the use of animals in this study were approved by the University Animal Care Committee (UACC) of Queen's University and complied with the guidelines of the Canadian Council of Animal Care (CCAC). The CCAC guidelines: Rats (CCAC, 2020) note that exposing rats to carbon dioxide for euthanasia is likely to cause pain and distress (Leach et al., 2004; Moody et al., 2014). Biological effects of blood loss: implications for sampling volumes and techniques. ... Rat 23‐25g < 10 ml/kg i.e. Materials. Ninety percent of these are rats, mice, fish, and fowl. jo�;���S |�����Y\*hdE�wQ��$0��D5�կ�=����A8�E����29�r�4 Assessments of institutional animal ethics and care programs are based on CCAC guidelines (animal care; types of animals; procedures; and program management) and assessment policies, as well as other relevant documents. CCAC resources. Broom. 2. Three Rs information and additional resources such as frequently asked questions (FAQs) are intended to support the implementation of the guidelines and to encourage institutions to evaluate new practices to enhance their animal ethics and care programs. methods, to achieve “euthanasia”, for rats and other laboratory animals are ongoing, as reflected in recent updates to the Canadian Council on Animal Care (CCAC) and American Veterinary Medical Association (AVMA) eu-thanasia guidelines [3, 4]. Guidelines for the use of animals in cancer research This is a selection of guidelines in the public domain that address the care and use of animals in cancer research, including the issue of … This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. the CCAC program are discussed in more detail in following sections. The main conflict of the story is when rats living in the city dump is mutated (from gases) Construction Cost Summary Template and wreaks havoc on the citizens of the city. Goals for successful euthanasia include techniques requiring minimal restraint, simplicity DZn��*U@��g �eb�xɟ+_2012l ���Hs�?ç�� *CU The Ratnoze is specialized for measuring solid fuel combustion emissions. Disinfectant: Lemon Quat TM, U974. 2010; McGuill MW, Rowan AN. This bibliography was generated on Cite This For Me on Tuesday, January 27, 2015 Rats Mice. The CCAC conducts assessment visits to each participating institution using animals. The guidelines contained within the Guide to Care and Use of Experimental Animals, vol 1, 2nd edition (1993) are currently being revised. Surveillance over the use of experimental animals, including wild vertebrates and invertebrates such as octopi and squid, is the responsibility of the Canadian Council on Animal Care (CCAC), a national, voluntary peer … Paper towel. %PDF-1.4 %���� e����7+���ob��/~"p��/���b���9��_A3)Q���K����:{L7\'V6���Y�f.pH'b�.S��Iɻw�(�f��=@+]��j�1cm����z�p@��.wZ�S��|{�]��W��i�>ѣp���f���K� 3. The CCAC guidelines: Rats provides information for investigators, animal care committees, facility manag- 4165 0 obj <>stream Y�)�f'�b T΍k ,��-��t�{8����\'L�V)�H)U=��l��}ߵ�8��Ǵ�v��s����w~�\� Zb zX�� ��g\H� @#DBZ�� h�D���] �9h� ^���9[CY?�|�b\�*AR��I�9x*! American Association of Swine Veterinarians (AASV) and National Pork Board (2008) On-Farm Euthanasia of Swine: Recommendations for the Producer.Des Moines IA: National Pork Board. The CCAC comprises 22 member organizations, whose presentatives include scientists, educators, veterinarians and delegates from industry and the animal welfare movement. Agricultural Research; CCAC guidelines on : the care and use of farm animals in research, teaching and testing; Other resources. Dust Pan. The CCAC euthanasia guideline (CCAC 2010) for animals used in science (all vertebrates and cephalopods) similarly requires killing methods to be “as distress free and painless as possible” (p.7) and result in rapid loss of consciousness. endstream endobj startxref 4128 0 obj <> endobj Normal core body temperature 37.5 –38.5oC Normal core body temperature 37.0 – 38.0oC Normal heart rate range 260 – 600 bpm Normal heart rate range 350 - 800 bpm. [CDATA[ �Z0:Bn�@q�-�^~�uX�OdcHކ��P?x�T�3i�//���.�kb����d{�$u�a&F�TLR�m8�{`e�Ǯ@]kX��!����[��t��`�z�H��˔���f� �`3��'��g���^�[��/��LI�z��F��2^�{�R���8��q�,�H[*��Spˌ�� ����Txw{�U5&�n��-e��5��6�]�΢���.���6���mv��m+���Y���[����=�$���a�e']R��X=/���BaQ��X���MxF!OCV��uOx�������G��x=I�J��Ęݧ����u�L�1�?�gd8\M��D1Y漶�s�d��9B�7o�X��7�B����0���.2,V�%R/�%y�UN���V�cBDUr}���޴�Y��!�Ӂ���^�[�]����:�w� �T%��N�S��=����9�{n�,��)�����۠ �{ֻ��Y�z��>�&^�6��3�y�;�Č51����^�����o��*��_ʱgˆ�Ǜg�ү�Uda�C��4:՚�x"����u*0��[� �USQ��}Y�����B�� �J�0?��Uc�����U�h廬}�Gx���e'&2������«�.���Xjrq�k �L 8%)�' Tel: 613-238-4031 (1998) Canadian Council on Animal Care, Canada; Guide for the care and use of laboratory animals. Purpose: to ensure each rat room and shoebox cage is maintained daily, weekly, and monthly care of rat rooms. rat to a temperature around 400C by placing the animal into a thermostatically warmed 'hot-box' (Conybeare et al., 1988), warming the tail under a heating lamp (Waynforth and Flecknell, 1992) or holding the tail in warm water for 1—2 minutes (Fallon, 1996) can induce tail vein dilation. Draw up, into the syringe and needle, the amount of solution to be administered. It is recommended to keep gestating and lactating rat dams, and pups up to 3‐4 weeks old, at the higher end of the recommended temperature range (24‐26C), as they have reduced thermoregulatory ability. Guidelines of the CCAC Since the first Guide to the Care and Use of Experimental Animals was published in 1968, the guidelines of the CCAC have steadily evolved in response to new information or … Assessments are based on several documents, including the CCAC guidelines and policies. The guidelines are based on expert peer advice and current interpretation of … Policy: Laurentian University and CCAC guidelines and Regulations. h�bbd```b`��"�A$� �d1��� ��L~�l�΀��� �,�� CCAC guidelines are intended to provide assistance in the implementation of Russell and Burch’s Three Rs (Replacement, Reduction and Refinement) principles for animals in science (Russell and Burch, 1959). In general terms the CCAC recommends that ... 17mm, width 17mm) tumour for rats. Pail. 4146 0 obj <>/Filter/FlateDecode/ID[<90C47C91D84E48C49C31241C391AB876><55AB78EB64346C4BA606F51FF4F157B1>]/Index[4128 38]/Info 4127 0 R/Length 102/Prev 1528554/Root 4129 0 R/Size 4166/Type/XRef/W[1 3 1]>>stream ILAR Journal Vol 31, Issue 4, p. 5-20; Rat - Blood draw video (saphenous vein, cardiac puncture) !�v���h��p��P�- Rats were sacrificed on the 7th and 14th days for pathological examination of the wound. Viscous adjuvants should never be given IV due to the risk of thrombosis and pulmonary embolism. emailE=('ccac@' + 'ccac.ca') MATERIALS 3.1. This is a user guide for the Ratnoze portable sampling system. �R�q�ei��2��&���}�h�� ���$�܏�t]���u��=�~��|n;A?���/����)�/��?�2,�r��d��\�����s�����'�%O�TOJ�bӹ�œ)�.�O'L���]�J���f��-"?��D�žL5m����̲�^ү̩�( e�����\hj�Ɨ�1sKH�f��|�b���QΒ�u�H�R� }�����@ZԪ�%Kf���!Ͻ�Pŋ"����������1�PP�&W��Dž/��!vp*����+�ETPt�����$�������H|�����s�� oÃc z� CCAC Guidelines: The current CCAC guidelines indicate that for cancer research the experiment must be designed with endpoints that minimize the potential for pain and/or distress. This SOP follows the CCAC guidelines for acceptable injection volumes in rodents. Aqueous adjuvants (or antigens without adjuvant) are usually given SC, IP, or IV to rats and mice, or SC, IM, or IV in rabbits. 0 �'� CCAC Publishes New Guidelines on Rats The CCAC guidelines: Rats is now available. In studies assessing rat aversion to euthanasia agents, These are the sources and citations used to research Chronic Restraint Stress in Rats. Compliance with CCAC guidelines and policies is a requirement to receive a CCAC Certificate of GAP – Good Animal Practice®, as determined by CCAC assessment panels. ... An investigator has developed a thorough analgesic protocol for experimental surgery on rats. When placing rats in a warmed box, it is essential that the Establish the basic requirements for each institutional program within the Canadian system oversight... Ccac recommends that... 17mm, width 17mm ) tumour for rats the syringe and needle, amount... Appropriate for emission measurements of brick kilns, and regulatory standards associated with the conduct of studies conduct! Ottawa, on, K2P 2R3 Tel: 613-238-4031 Fax: 613-238-2837 Email:

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